Medications

Somatic Treatment for Schizophrenia



Antipsychotic medications were first introduced by two French researchers in 1952. Prior to that time there were no effective treatments for schizophrenia. The first antipsychotic medication was chlorpromazine (thorazine). It was found to control the most serious Positive Symptoms of schizophrenia. Antipsychotic medications are often called major tranquilizers, but they do vary on the degree to which the client feels sedated.

Antipsychotic medications are effective in controlling psychotic symptoms for the major of people with schizophrenia, however, they have a number of very serious side effects that can be both uncomfortable and even dangerous. Side effects need to be monitored and managed effectively. Many consumers will discontinue their medication in order to avoid the side effects, and this can result in exacerbation of their symptoms and often rehospitalization.

The most common side effects are:

Tardive Dyskinesia: This is abnormal involuntary movement, often of the mouth and tongue. Tardive dyskinesia can become permanent.

Anticholinergic effects: These include dry mouth, tachycardia (rapid heartbeat), blurry vision, constipation.

Extrapyramidal effects: Refers to a number of disorders related to motor control, including:


Traditonal Antipsychotic medications include:


The new atypical antipsychotic medications used for treatment-refractory (those not responding to traditional drugs) consumers are:

(These medications also have fewer extrapyramidal effects)